Publications

A library of MiMICs allows tagging of genes and reversible spatial and temporal knockdown of proteins in Drosophila.

eLife 4:e05338

A voltage gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis.

PLoS Biology 13:e1002103

A genetic toolkit for tagging intronicMiMICs containing genes.

eLife4:e08469

Complementary Expression of Ig superfamily ligands and receptors in synaptic pairs in the Drosophila visual system.

Cell163:1770-1782

Control of synaptic connectivity in Drosophila by a network of IgSF surface proteins.

Cell163:1770-1782

Independent amino acid residues in the S2 pocket of falcipain-3 determine its specificity for P2 residues in substrates.

Mol Biochem Parasitol. 202(2):11-22. doi: 0.1016/j.molbiopara.2015.09.005.

A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation.

Journal of Immunology

Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy.

Autophagy. 2015 Aug 27:0. PMID: 26313894

IRGM governs the core autophagy machinery to conduct antimicrobial defense.

Molecular Cell. Volume 58, Issue 3, p507-521, 7 May,

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.

Nature Communication. 2015 Oct 27;6:8620. doi: 10.1038/ncomms9620