CSIR - Centre for Cellular & Molecular Biology
Council of Scientific and Industrial Research
The Innovation Engine of India
IRGM governs the core autophagy machinery to conduct antimicrobial defense.
Molecular Cell. Volume 58, Issue 3, p507-521, 7 May,
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.
Nature Communication. 2015 Oct 27;6:8620. doi: 10.1038/ncomms9620
The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.
Journal of Molecular Biology (https://doi.org/10.1016/j.jmb.2015.01.019)
Structural organization of the dynein-dynactin complex bound to microtubules.
Nature Structural & Molecular Biology (https://doi.org/10.1038/nsmb.2996)
Mutations in the predicted active site of Xanthomonas oryzae pv. oryzae XopQ differentially affect virulence, suppression of host innate immunity and induction of HR in a non-host plant.
Mol. Plant Microbe Interact. 28, 195-206.
Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nature Commun. 6:7552 doi: 10.1038/ncomms8552.
Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase.
Chemistry & Biology 22, 1577-1587.
The Mycobacterium tuberculosis protein pair PE9 (Rv1088) - PE10 (Rv1089) forms heterodimers and induces macrophage apoptosis through TLR4
Cellular Microbiol 17(11): 1653-1669
Dissecting the Membrane Cholesterol Requirement for Mycobacterial Entry into Host Cells
Chem Phys Lipids 189:19-27
Identifying novel mycobacterial stress associated genes using a random mutagenesis screen in Mycobacterium smegmatis
Gene 574(1):20-27