CCMB

CSIR - Centre for Cellular & Molecular Biology
Council of Scientific and Industrial Research

The Innovation Engine of India

Ministry of Science & Technology, Govt. of India

The People

G Umapathy

G Umapathy

Chief Scientist
+91-040-24006422
guma@ccmb.res.in

Research Interests

Habitat fragmentation is the primary cause of the present extinction crisis in tropics. Our group is interested in understanding its impact on the survival of many endangered species in human-dominated landscapes by studying behaviour, demography, reproductive and stress physiology, and genomics. Our group is also interested in developing various biotechnological tools in biodiversity conservation including eDNA tools in the aquatic ecosystem for studying ecosystem services.

Selected Publications

Shivakumara Manu, Govindhaswamy Umapathy, 2024. Deep sequencing of extracellular eDNA enables total biodiversity assessment of ecosystems, Ecological Indicators, 156, 2024,111171, https://doi.org/10.1016/j.ecolind

Kuderna LFK, Umapathy G, et al. 2023. A global catalog of whole-genome diversity from 233 primate species. Science. 2023; 380:906-913.

Hong Gao, Umapathy, G. et al. 2023. The landscape of tolerated genetic variation in humans and primates. Science, 380, eabn8153. DOI: 10.1126/science.abn8197.

Kuderna LFK, Umapathy G, et al. 2024. Identification of constrained sequence elements across 239 primate genomes. Nature. 2024 ;625:735-742. doi: 10.1038/s41586-023-06798-8.

Kumar, V. Manu, S.; Caroline, K. Sekhar, A. Mamta, S.K. Sandeep, M., Wasmimuddin Senthilkumaran, B. Umapathy, G. 2022. Discovery of 16-Androstenes (Androstenone and Androstenol), Their Synthesis Pathway, and Possible Role in Reproduction of Mouse Deer (Moschiola indica). Cells 2022, 11, 3837. https://doi.org/10.3390/cells11233837

Education & Experience

P.G:

Wildlife Biology ; Bharathidasan University Thiruchirapalli, India ; 1990

Ph.D:

Impacts of habitat fragmentation on the arboreal mammals in the wet evergreen forests of Western Ghats, South India ; Salim Ali Centre for Ornithology and Natural History, Coimbatore, India ; 1998

Post.Doc:

Survey and status distribution of crab-eating macaques in Nicobar Islands ; Mysore University ; 1999-2000

 

Experience:

Since 2000 working in the Laboratory for the Conservation of Endangered Species (LaCONES, CCMB) towards wildlife conservation using modern biotechnological tools.

Team Members

team-members-pic
Vinod Kumar
Vinod Kumar

Sr. Technical Officer(1)

Sr. Technical Officer(1)

Vinay Teja
Vinay Teja

Junior Research Fellow

Junior Research Fellow

Gudimella Anusha
Gudimella Anusha

Junior Research Fellow

Junior Research Fellow

Gopi Krishnan
Gopi Krishnan

Junior Research Fellow

Junior Research Fellow

M S Ram
M S Ram

Senior Research Associate

Senior Research Associate

Manisha Ray
Manisha Ray

Junior Research Fellow (Project)

Junior Research Fellow (Project)

Anuja Pandey
Anuja Pandey

Junior Research Fellow (Project)

Junior Research Fellow (Project)

Neeldeep Ganguly
Neeldeep Ganguly

Junior Research Fellow (Project)

Junior Research Fellow (Project)

Gayatri Divekar
Gayatri Divekar

Junior Research Fellow (Project)

Junior Research Fellow (Project)

Himanshu Kothari
Himanshu Kothari

Junior Research Fellow (Project)

Junior Research Fellow (Project)

Abhilash Nair
Abhilash Nair

Project Associate-I

Project Associate-I

Mamidala Srilakshmi
Mamidala Srilakshmi

Project Associate-I

Project Associate-I

Publications

Title

Journal

Year

Genetic Diversity, Geographical Structure, and Demographic History of the Kashmir Gray Langur (Semnopithecus ajax)
International Journal of Primatology
2024
Cyanobacterial genomes from a brackish coastal lagoon reveal potential for novel biogeochemical functions and their evolution
Journal of Molecular Evolution
2024
Is It There? - Estimating the invasion of armored sailfin catfish (Pterygoplichthys Sp.) in the water bodies of Eastern Ghats, India using the eDNA approach.
Environmental DNA
2024
Deep sequencing of extracellular eDNA enables total biodiversity assessment of ecosystems
Ecological Indicators
2024
Distribution, social organization, and management of Semnopithecus johnii: An umbrella species of fragmented landscape of the Western Ghats
Biotropica
2023
Identification of constrained sequence elements across 239 primate genomes
Nature
2023
Phylogenetic insights on the delineation of Mysore and Malabar subspecies of the Grey Slender Loris Loris lydekkerianus in southern India
Journal of Threatened Taxa
2023
From Captivity to Conservation Success: A Review on the Mouse Deer Breeding Program and its Implications for Biodiversity Preservation
Journal of Endocrinology and Reproduction
2023
The landscape of tolerated genetic variation in humans and primates
Science
2023
A global catalog of whole-genome diversity from 233 primate species
Science
2023
Measures of Adrenal and Gonadal Hormones in Relation to Biological and Management Factors among Captive Red Pandas in Indian Zoos
Animals
2023
Development of an enzyme immunoassay to measure urinary and faecal 5𝛼-androst-16-en-3-one in pigs
MethodsX
2023
Development of a species-specific qPCR assay for the detection of invasive African sharptooth catfish (Clarias gariepinus) using environmental DNA
Biological Invasions
2022
Discovery of 16-Androstenes (Androstenone and Androstenol), Their Synthesis Pathway, and Possible Role in Reproduction of Mouse Deer (Moschiola indica)
Cells
2022
Genetic Diversity and Population Structure in Western Hoolock (Hoolock hoolock) Gibbons in India
International Jounral of Primatology
2022
Impacts of Livestock Grazing on Fecal Glucocorticoid Levels and Gastrointestinal Parasite Prevalence in Blue Sheep in Spiti Valley, Western Himalayas.
Journal Of Endocrinology And Reproduction
2022
Environmental DNA as a tool for biodiversity monitoring in aquatic ecosystems – a review
Journal of Threatened Taxa
2022
A practical method for storage, preservation and transportation of anuran urine samples using filter paper for hormone analysis.
MethodX
2021
Genetic effects of long-term captive breeding on the endangered pygmy hog
PeerJ
2021
Trade-offs between reducing complex terminology and producing accurate interpretations from environmental DNA: Comment on “Environmental DNA: What’s behind the term?” by Pawlowski et al.(2020).
Molecular Ecology
2021
Understanding the phylogenetics of Indian Hoolock gibbons – Hoolock hoolock and H. leuconedys
International Journal of Primatology, https://doi.org ./10.1007/s10764-021- 00212-8
2021
Non-Invasive Reproductive Hormone Monitoring in the Endangered Pygmy Hog (Porcula salvania)
Animals https://doi.org/10.3390/ani11051324.
2021
Non-invasive monitoring of glucocorticoid metabolite concentrations in native Indian, as well as captive and re-wilded tigers in South Africa
General and Comparative Endocrinology, 2021,Vol 308,113783, https://doi.org/10.1016/j.ygcen. 2021.113783.
2021
Diet drives differences in reproductive synchrony in two sympatric mountain ungulates in the Himalaya
Frontiers in Ecology and Evolution 9:647465. doi:10.3389/fevo.2021.647465(accepted)
2021
Variation in predicted COVID?19 risk among lemurs and lorises.
American Journal of Primatology, e23255. https://doi.org/10.1002/ajp.23255.
2020
Effect of Dietary Inclusion of Live Microbial Cultures on Faecal Glucocorticoid Metabolites in Safari Asian Elephants.
Indian Journal of Animal Research. DOI: 10.18805/ijar.B-4124
2020
Comparison of tigers
Plos One
2019
Non-invasive monitoring of steroid hormones in wildlife for conservation and management of endangered species
Indian Journal of Experimental Biology
2019
Hair Cortisol in Sheltered Cows and Its Association with Other Welfare Indicators.
Animals
2019
Physiological stress responses of tigers due to anthropogenic disturbance especially tourism in two central Indian tiger reserves.
Conservation Physiology
2019
Non-Invasive Assessment of Physiological Stress in Captive Asian Elephants.
Animals
2019
Land Use Change Increases Wildlife Parasite Diversity in Anamalai Hills, Western Ghats, India
Scientific Reports
2019
Cross-specific markers reveal retention of genetic diversity in captive-bred pygmy hog, a critically endangered suid
Conservation Genetics Resources
2018
Physiological stress responses in wild Asian elephants Elephas maximus in a human-dominated landscape in the Western Ghats, southern India. 2018,
General and Comparative Endocrinology, doi: https://doi.org/10.1016/j.ygcen.2018.05.009
2018
Correlates of physiological stress and habitat factors in reintroduction-based recovery of tiger (Panthera tigris) populations.
Hystrix, the Italian Journal of Mammalogy, https://doi.org/10.4404/hystrix-00063-2018
2018
Non-invasive hormone monitoring as an emerging tool in wildlife conservation 2017. In `Updates on Integrative Physiology and Comparative Endocrinology Modern Biology`
Published by Banaras Hindu University, Banaras.pp 88-108.
2017
Prevalence and Co-occurrence of Gastrointestinal Parasites in Nilgiri Langur (Trachypithecus johnii) of Fragmented Landscape in Anamalai Hills, Western Ghats, India.
Current Science 113: 2194-2200.
2017
First record of Eurasian otter Lutra lutra in the Anamalai Hills, southern Western Ghats, India 2017.
IUCN Otter Spec. Group Bull. 35: 46-56.
2017
Prevalence of gastrointestinal parasites in civets of fragmented rainforest patches in Anamalai hills, Western Ghats, India.
Journal of Parasitlogy
2016
Non-invasive monitoring of reproductive and stress hormones in the endangered red panda (Ailurus fulgens fulgens).
Animal Reproduction Science
2016
Genetic Diversity and Structure among Isolated Populations of the Endangered Gees Golden Langur in Assam, India.
PLoS ONE 11(8): e0161866. doi:10.1371/journal.pone.0161866
2016
Mammalian gastrointestinal parasites in rainforest remnants of Anamalai Hills, Western Ghats, India.
Journal of Biosciences. 40 399-406 DOI 10.1007/s12038-015-9517-5
2015
Glucocorticoid stress responses of tigers in relation to anthropogenic disturbance in Sariska tiger reserve, India.
PLOS ONE 10.1371/ Journal.pone.0127626
2015
Endocrine Profiling of Endangered Tropical Chelonians Using Non-Invasive Fecal Steroid Analyses.
Chelonian conservation Biology 2015, 14(1):1-7
2015
Non-invasive assessment of faecal progestagens and pregnancy detection in Himalayan Musk Deer (Moschus chrysogaster).
Theriogenology, Doi. :10.1016/j.theriogenology. 2015.09.009.
2015
Pre-historic and recent vicariance events shape genetic structure and diversity in endangered lion-tailed macaque in the Western Ghats: Implications for conservation.
PLoS ONE 10(11): e0142597. doi:10.1371/journal. pone.0142597.
2015
Non-invasive assessment of reproductive status and stress in captive Asian elephants in three south Indian zoos.
General and Comparative Endocrinology, 201: 37-44
2014
Observations on reproductive performance of Indian mouse deer (Moschiola indica) in captivity.
Current Science 106:439-441.
2014
The Lion-tailed macaque: A case study in the impacts of forest fragmentation.
In: A Textbook of Wildlife Ecology and Conservation, M.Balakrishnan (ed). Scientific Publishers, Jodhpur. [In press]
2014
Human presence increases parasitic load in endangered lion-tailed macaques (Macaca silenus) in its fragmented rainforest habitats in southern India.
PLOS ONE 10.1371/journal.pone.0063685.
2013
Research in Habitat Fragmentation: Are We Moving in the Right Direction?
Journal of Primatology 2: e119. doi:10.4172/2167-6801.1000e119
2013
Averting biodiversity collapse in tropical forest protected areas.
Nature, 2012 doi:10.1038/nature11318
2012
The 34,XY(1),der(13) Chromosome Constitution with Loss of Y(2) Is Associated with Unilateral Testicular Hypoplasia in the Endangered Indian Blackbuck Antelope (Antilope cervicapra).
Sex Dev. 2012 Jul 25:240-246.
2012
Detection of pregnancy and fertility status in big cats using an enzyme immunoassay based on 5?-pregnan-3?-ol-20-one.
Gen Comp Endocrinol. 2012. doi: S0016-6480(12)00415-7. 10.1016/j.ygcen.2012.10.009.
2012
Conservation-oriented captive breeding of primates in India: is there a perspective?
Current. Science, 103 : 1399-1400.
2012
Impact of Habitat Fragmentation on the Demography of Lion-tailed Macaque (Macaca silenus) Populations in the Rainforests of Anamalai Hills, Western Ghats, India
International Journal of Primatology 32, 889-900
2011
Monitoring of vultures in Andhra Pradesh. In Bhupathy et al (eds). Status of Indian birds and their conservation.
Proceedings of the First International Conference on Indian Ornithology, SaCON, Coimbatore, India. Pp 195-198.
2011
Impact of Habitat Fragmentation on the arboreal mammals.
Lambert Academic Publishing, ISBN 978-3-8465-5114-1. p. 148.
2011
Long-tailed macaques (Crab-eating macaque, Macaca fascicularis umbrosa) in Nicobar Islands, India
Recent Trends in Biodiversity in Andaman and Nicobar Islands. Zoological Survey of India, Govt. of India. pp 449-454.
2010
Status and distribution of vultures in Andhra Pradesh, India
Forktail 25: 163-166.
2009
Semen characteristics, semen short term storage and successful artificial insemination following oestrous synchronisation in Blackbuck.
Reproduction Fertility and Development 21: 749-756.
2009
Yohimbine antagonizes the anaesthetic effects of ketamine-xylazine in captive Indian wild felids.
Veterinary Anaesthesia and Analgesia, 36, 34-41.
2009
Tolazoline antagonizes ketamine-xylazine anaesthesia in an endangered Black buck (Antilope cervicapra)
European Journal of Wildlife Research. 55:357-361.
2009
Seasonal variations in semen characteristics, semen cryopreservation, estrus synchronization, and successful artificial insemination in the spotted deer (Axis axis).
Theriogenology. 67(8):1371-8.
2007
Anesthesia induced by administration of xylazine hydrochloride alone or in combination with ketamine hydrochloride and reversal by administration of yohimbine hydrochloride in captive Axis deer (Axis axis).
Am J Vet Res. 68 :20-4.
2007
Estrus behavior and fecal steroid profiles in the Asiatic lion (Panthera leo persica) during natural and gonadotropin-induced estrus.
Anim. Reprod. Sci. 101:313-25.
2007
Conservation of Mega cats conservation: Problems and Approach.
In: You Deserve, We Conserve (Eds. Pandit, MW, Shivaji, S and Lalji Singh), I.K International Publishing House Pvt. Ltd. New Delhi p 7-18
2007
Chemical capture of wild animals.
In: You Deserve, We Conserve (Eds. Pandit, MW, Shivaji, S and Lalji Singh), I.K International Publishing House Pvt. Ltd. New Delhi p 77-82.
2007
Semen characteristics of the captive Indian white-backed vulture (Gyps bengalensis).
Biology of Reproduction, 73: 1039-1045.
2005
Semen characteristics, cryopreservation and successful artificial insemination in the Blue Rock Pigeon (Columba livia) as model for endangered bird species.
Theriogenology 62: 139-153.
2004
Status and distribution of crab-eating macaque in Nicobar Islands in India.
International Journal of Primatology. 24 (2): 281-293.
2003
Conservation of Wild animals by assisted reproduction and Molecular marker technology.
J. Exp. Bio. 41:710-723
2003
Development and characterization of ten novel microsatellite markers from Chital deer (Cervus axis) and their cross amplification in other related species.
Molecular Ecology Notes 3: 607 - 609.
2003
Impacts of forest fragmentation on lion-tailed macaque and Niligiri langur in Western Ghats, South India.
In \"Primates in fragments\". Laura K. Marsh (Ed) Kulwer Academic / Plenum Publishers, New York.
2002
The occurrence of arboreal mammals in the rain forest fragments in Anamalai Hills in the Western Ghats, South India.
Biological Conservation 92: 311-319.
2000
Impacts of habitat fragmentation on time budget and feeding ecology of lion-tailed macaque (Macaca silenus) in rain forest fragments of Anamalai hills, south India.
Primate Report, 58: 67-82.
2000
Food habits and activity pattern of common otter Lutra lutra nair at Pichavaram,Tamil Nadu, South India,
J. Bombay Nat. His. Soc. 97(3): 367-369.
2000
The Demography of the Lion-Tailed Macaque (Macaca silenus) in rain forest fragments in the Anamalai Hills in the Western Ghats, South India,
Primates 41 (2): 119 - 126.
2000
Home range and habitat use by Indian Grey mongoose and small Indian civets in Nilgiri Biosphere Reserve India.
In ENVIS Bulletin: Wildlife and Protected Areas, Mustelids, Viverrids and Herpestides of India. S.H.Hussain (Ed) Vol 2 (2):
1999
Occurance of the Indian Python (Python molurus) near Coimbatore, Tamil Nadu.
Cobra, 31:19.
1998
Movement of Nilgiri langur in the Fragmented rain forest of Anamalai Hills.
J. Bombay Nat. His. Soc., 95: 123.
1996
Comparative study on the haematology and blood chemistry of blue rock pigeon and spotted dove.
PAVO 35 (127): 23-35.
1996
Meat eating by lion-tailed macaque (Macaca silenus).
J. Bombay Nat. His. Soc. 93: 79.
1995
A preliminary study on feeding ecology of common otter (Lutra lutra nair)
IUCN Otter Spec.Group Bull. 11: 31-33.
1995
A study on the management and conservation of the small mammals in fragmented rain forests of Western Ghats, South India. A preliminary report.
Primate conservation, 16:53-58.
1995
A new record of little pied flycatcher from Nilgiri Biosphere Reserve.
News letter for Birdwatchers, 34(2): 33.
1994
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